CoCrystEO™

Product Introduction

CoCrystEO™ is a revolutionary feed additive engineered using crystal technology to overcome the volatility and instability of conventional essential oils. By modifying the physicochemical properties of thymol and carvacrol, CoCrystEO™ creates a stable crystalline structure without relying on traditional coating or encapsulation.
This NOVEL and next-generation technology ensures that active compounds survive aggressive feed processing (pelleting/expanding) and are delivered predictably to the gastrointestinal tract to support gut integrity and growth performance.
In animal studies, CoCrystEO™ supplementation at practical inclusion levels (ONLY 30–60 mg/kg in pure form) was associated with favorable changes in growth-related parameters and gut structural development in broilers, and enhanced gut fermentation and intestinal integrity in weaned piglets under low-zinc, antibiotic-free conditions

Why CoCrystEO™?

CoCrystEO™ is designed for feed systems where essential oil performance is often compromised.
The crystal structure increases melting point to approximately 123°C, compared with around 50°C for thymol and near ambient temperature for carvacrol, supporting greater resilience during pelleting and expanding processes.

Under stressed storage conditions (40°C, 75% relative humidity), CoCrystEO™ maintained more than 97% assay retention over three months, while a benchmark encapsulated essential oil declined to approximately 75%, indicating improved stability of active compounds under real-world logistics and storage conditions.

CoCrystEO™ also demonstrates rapid dispersion behavior. At a practical inclusion rate, the product fully dissolved in water within three minutes, whereas conventional essential oil and encapsulated formats showed minimal dissolution even after extended time. This supports uniform distribution and reduces variability in gut exposure.

Mode of Action

Crystal engineering reduces volatility and stabilizes thymol and carvacrol, helping preserve active content during feed processing and storage.
Once ingested, the stabilized delivery of thymol and carvacrol contributes to a more consistent exposure of active compounds in the gastrointestinal tract, which is reflected in gut morphology and fermentation markers observed in animal studies

Key Benefits

  • Improved essential oil stability during feed processing and storage
  • Higher melting point and reduced volatility support use in pelleting/expanding and reduce loss during handling, with demonstrated retention under stressed storage compared with an encapsulation benchmark.
  • Faster dispersion and more uniform delivery in feed and water systems
    Rapid dissolution at practical inclusion and reduced unpleasant odor are positioned to allow more flexible application while minimizing common essential oil handling constraints.
  • Demonstrated effects on gut structure in broilers and enhanced fermentation output and intestinal integrity in weaned piglets, with associated changes in growth-related parameters.

Frequently Asked Questions

Many essential oils show promising activity on paper but lose effectiveness during feed processing, storage, or uneven mixing. CoCrystEO™ is designed to reduce these losses by improving stability, dispersion, and consistency of essential oil delivery from production to the gut. 

CoCrystEO™ is positioned as a gut-focused nutritional solution. In animal studies, its effects were reflected not only in growth performance but also in intestinal structure and fermentation markers, which are closely linked to nutrient utilization and resilience under stress.

CoCrystEO™ has been evaluated in weaned piglets under low-zinc, antibiotic-free conditions. Improvements in intestinal structure and fermentation markers support its use as part of a broader nutritional strategy aimed at maintaining gut health when pharmacological zinc oxide or antibiotics are reduced. 

Compared with conventional essential oils, the crystal structure reduces volatility  and odor intensity, which may help minimize palatability issues commonly associated with essential oil inclusion.