Functional Animal Nutrition
- Replace antimicrobial growth promoter
- Enhance intestinal barrier health and upregulate endogenous immunity
- Increase nutrient digestibility
- Improve meat, egg and dairy milk production yield and quality
- Promote industry sustainability
Vitamins
25-Hydroxyvitamin D3 (or Calcifediol) is an endogenous Vitamin D metabolite, naturally produced in the liver of animals through hydroxylation of Vitamin D 3 (Cholecalciferol). It is the main circulatory Vitamin D in the blood stream before further conversion to Calcitriol, the ultimate bioactive hormonal form of Vitamin D in the kidney, that promotes the uptake of Calcium and Phosphorous in the intestine.
Suprema-D ® is a form of 25-Hydroxyvitamin D3 feed additive, stable under feed processing conditions, and 100% derived from plant source raw materials rather than from animal source. It is formulated for application in multivitamin mineral premixes, and complete feed, particularly for young animals, breeder animals, and layers. It is also beneficial for grower phase animals. Numerous animal studies suggest that Suprema-D® (25-Hydroxyvitamin D3) is 3 to 5x more bio-efficacious than standard Vitamin D3.
Benefits
Suprema-D ® effectively makes up typical insufficiencies of Vitamin D3 in nutritional formulations, typically in gilt, sow, piglet, and layer diets. It significantly strengthens skeleton, bone health, and egg shell to bolster high reproduction, growth and laying performance. It permeates blood-placental barrier, hence effectively upholds bone growth in the critical fetal stage.
Vitamins
25-Hydroxyvitamin D3
25-Hydroxylcholecalciferal is an endogenous vitamin D metabolite, naturally produced in the liver of animals through hydroxylation of vitamin D3 (Cholecalciferol). It is the main circulatory Vitamin D, in the blood stream before further conversion to Calcitriol, the ultimate bioactive hormonal form of Vitamin D, in the kidney, that promotes the uptake of Calcium and Phosphorous in the intestine.
Suprema-D ® is a form of 25-Hydroxyvitamin D3, feed additive, stable under feed processing conditions, produced from non-animal source. It’s particularly beneficial for young animals & breeder animals, and also improves performance of grower – phase animals. Numerous animal studies suggest that 25-Hydroxyvitamin D3, is 3 to 5x more bioefficacious than standard Vitamin D3.
Note:
25-Hydroxyvitamin D3’s synonyms: 25-Hydroxycholecalciferol and calcifediol, or in short 25-OH-D3
Amino Acids
A metabolically stable analogue of N-acetylglutamate (NAG) that activates carbamyl phosphate synthetase (CPS) to accelerate urea cycle.
Benefits
Supplementation of exogenous NCG to animals can boost endogenous Arginine synthesis and metabolism to produce NO (nitric oxide) and polyamines via urea circulation. Many studies demonstrated that NCG addition to feed is able to increase milk yield and quality, promote calves’ growth performance, improve meat quality & slaughter yield. It also strengthens heat stress tolerance, and its ability to boost sow’s reproductivity, promote growth of piglets and growing pigs, and improve meat quality.
Antimicrobial Solutions
Lactitide
Extracted metabolites of lactobacillus plantarum and etc., containing a kind of lasso-like microcin peptide (tertiary structure shown as below).
This endogenous peptide has a strong bacteriostatic and bacteriocidal effect against many standard and clinical strains of E. Coli and Salmonella with MIC and MBC shown below.
To E. Coli To Salmonella
MIC = 0.03-0.50μg/mL MIC = 0.03-0.06μg/mL
MBC= 0.25-2.00 μg/mL MBC= 0.125-0.250μg/mL
The composition is pH-stable, and thermostable.
A comprehensive piglet study demonstrated that Lactitide enabled better growth performance, lower inflammation level, healthier intestinal barrier, and more robust gut microflora than antibiotic treatment, with less than 1/10 dosage of antibiotic growth promotents.
An E. Coli and Salmonella challenge broiler study demonstrated that Lactitide exhibited strong efficacy in containing pathogenic infection, recovering villi/crypt structure, alleviating inflammation, resulting in improved growth performance versus antibiotic growth promotent treatment at less than 1/10 dosage.
Bacitide
Extracted metabolites of bacillus subtilis and etc., containing a 37-amino acid sublancin peptide (tertiary structure shown as below).
This endogenous peptide has a strong Bacteriostatic / Bacteriocidal effect against standard and clinical strains of clostridium perfringens and staphylococcus aureus with MIC and MBC shown below.
To staphylococcus aureus To clostridium perfringens
MIC = 1.3 μg/mL MIC = 0.8 μg/mL
Antimicrobial Solutions
Ceretide is a series of yeast-based products containing different bioactive Antimicrobial Peptides (AMPs) catering to different animal species targeting different pathogens. These AMPs’ tertiary structures are clearly definable through advanced QC techniques, hence the quality and performance consistency of the products can be assured.
Higher Bioactivities = Lower Application Dosages = Cost Effectiveness
Ceretide™ S
Yeast based product containing potent Antimicrobial Peptides that specifically inhibit prevalent strains of E. Coli and Salmonella spp, and downregulate Gpathogen-induced inflammatory response.
Together with acidifiers, it is expected to well address the bacteria-induced diarrhea problem hence improve survival rates of weaning piglets & early nursing piglets, leading to improved overall growth performance. It also eliminates or reduces reliance on Zinc Oxide, Essential Oils, and Antibiotic Growth Promotants (AGPs). It also synergizes with swine vaccination by elevating specific antibody titers.
Ceretide™ B
Another yeast based product containing potent Antimicrobial Peptides that specifically inhibit prevalent strains of type A & C Clostridium Perfringens spp in broilers enabling replacement of broad spectrum feed antibiotics and probiotics. It also synergizes with poultry vaccination by elevating specific antibody titers, and upregulates cellular immunity.
Commercial applications also evidenced that it can induce heat stress tolerance, and elevate protein digestibility in energy-reduced and protein-reduced diets without sacrificing growth performance.
Ceretide™ L
Yeast based product containing potent Antimicrobial Peptides that specifically inhibit prevalent strains of E. Coli and Salmonella spp for layer hens and enhance oviduct & intestinal health. It reduces wet dropping, and dirty/broken egg rates by 3 – 8%. Animal trials and commercial experiences evidenced improvement in laying rates and peak laying periods extended by weeks, without the use of feed antibiotics.
It also synergizes poultry vaccination by elevating specific antibody titers.
Ceretide™ AQ
A different yeast-based product containing bioactive peptides targeting aquaculture species to boost innate intestinal immunity for stronger biotic stress tolerance and promote growth performance plus feed efficiency.
Saccharotide™
A special yeast extract product derived from fresh spent brewer’s yeast with consistent quality and sustainable large supply. Applicable for all animal species, esp. great for aquafeed and pet food, as a premium protein ingredient.
The key differentiation points lie in:
80% crude protein
8% crude ash
8% moisture
Low Crude Ash
Saccharotide™ contains minimal crude ash, ensuring higher digestible energy and better nutritional value for animals.
Low Bio-Amines
With very low levels of bio-amines, Saccharotide™ reduces the risk of digestive disturbances, promoting gut health and well-being.
Cost-Competitive
Saccharotide™ offers excellent nutritional benefits at a competitive price, providing an efficient and economical solution.
